Immunological factors for chronic rejection and the methods for the prevention of chronic allograft nephropathy

For the prevention of the immunological chronic rejection, HLA-DRB1 allele matching, enough immunosuppression in the induction phase and pathological diagnosis by non-episode and protocol biopsy are the effective methods. For the prevention of the non-immunological chronic rejection, treatments for hypertension, hyperlipidemia and hyperfiltration are the effective treatments.