Post-thyroidectomy hypocalcemia. Incidence and risk factors |
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| Authors: | D J Wingert S R Friesen J I Iliopoulos G E Pierce J H Thomas A S Hermreck |
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| Affiliation: | 1. From the Division of Breast & Thyroid Surgical Oncology, Department of Surgery, College of Medicine, St. Vincent''s Hospital, The Catholic University of Korea, Gyeonggi-do, Republic of Korea.;1. The Ohio State University College of Medicine, Columbus, OH 43210, USA;2. Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center and James Cancer Hospital, Columbus, OH 43210, USA;3. Department of Biomedical Informatics Center for Biostatistics at the Ohio State University College of Medicine, Columbus, OH 43210, USA |
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| Abstract: | Two hundred twenty-one patients undergoing thyroidectomy were analyzed for factors increasing the risk of postoperative hypocalcemia. Eighty-three percent of all patients experienced hypocalcemia postoperatively, with 13 percent requiring some treatment for symptoms. Patients with advanced thyroid cancer, Graves' disease, or other manifestations of preoperative hyperthyroidism had significantly increased rates of hypocalcemia compared with patients with small cancers or benign euthyroid disease. Total thyroidectomy, repeat thyroidectomy, and thyroidectomy plus neck dissection all significantly increased the incidence of permanent hypocalcemia, whereas lobectomy or subtotal thyroidectomy for benign euthyroid disease were low risk operations. Inadvertent excision of more than one parathyroid gland during thyroidectomy also significantly increased the rate of permanent hypocalcemia. |
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