Oral cholera vaccine use in Zanzibar: socioeconomic and behavioural features affecting demand and acceptance |
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Authors: | Christian Schaetti Raymond Hutubessy Said M Ali Al Pach Mitchell G Weiss Claire-Lise Chaignat Ahmed M Khatib |
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Affiliation: | (1) Department of Public Health and Epidemiology, Swiss Tropical Institute, Socinstrasse 57, 4002 Basel, Switzerland;(2) Initiative for Vaccine Research, World Health Organization, 20, avenue Appia, 1211 Geneva 27, Switzerland;(3) Public Health Laboratory Ivo de Carneri (PHL-IdC), Ministry of Health and Social Welfare of Zanzibar, 122 Chake-Chake, Pemba, United Republic of Tanzania;(4) International Vaccine Institute, SNU Research Park, San 4-8, Bongcheon-7-dong, 151-919 Kwanak-gu, Seoul, Korea;(5) Global Task Force on Cholera Control, World Health Organization, 20, avenue Appia, 1211 Geneva 27, Switzerland;(6) Ministry of Health and Social Welfare of Zanzibar, PO Box 236, Zanzibar, United Republic of Tanzania |
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Abstract: |
Background Cholera remains a serious public health problem in low-income countries despite efforts in the past to promote oral rehydration therapy as major treatment. In 2007, the majority of worldwide cases (94%) and deaths (99%) were reported from Africa. To improve cholera control efforts in addition to maintaining and improving existing water supply, sanitation and hygiene behaviour measures, the World Health Organization has recently started to consider the use of vaccines as an additional public health tool. To assess this new approach in endemic settings, a project was launched in Zanzibar to vaccinate 50,000 individuals living in communities at high risk of cholera with an oral two-dose vaccine (Dukoral?). |
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