Successful transplantation of four kidney grafts from two small pediatric donors with anuric acute renal failure into adult recipients |
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| Authors: | Martina Koch Daniel Kraus Simone Boedecker-Lips Jens Mittler Ineke Tieken Julia Weinmann-Menke |
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| Affiliation: | 1. Universitätsmedizin Mainz, Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Mainz, Germany;2. Universitätsmedizin Mainz, 1. Medizinische Klinik, Nephrologie, Mainz, Germany;3. Eurotransplant, Leiden, The Netherlands |
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| Abstract: | Background Kidneys from infants with anuric acute kidney injury (AKI) only rarely get accepted for transplantation despite encouraging data that such kidneys can have very good long-term outcome. Methods We report the transplantation of four kidney grafts from two pediatric donors (3 and 4 years) with anuric acute kidney injury as single kidneys into four adult recipients. Results All grafts gained function within 14 days posttransplantation, only one recipient needed dialysis after transplantation. None of the recipients suffered from surgical complications. One month after transplantation, all recipients were free of dialysis. Estimated glomerular filtration rates (eGFR) 3 months after transplantation were 37, 40, 50, and 83 mL/min/1.73 m2. eGFR increased further through month 6, reaching 45, 50, 58, and 89 mL/min/1.73 m2. Conclusion These cases highlight the feasibility of successful transplantation of single pediatric kidney grafts into adult recipients despite anuric AKI of the donor. |
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| Keywords: | pediatric kidney transplant |
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