Splenic infarction associated with sorafenib use in a hepatocellular carcinoma patient |
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| Authors: | Kim Sang Ock Han Sang Young Baek Yang Hyun Lee Sung Wook Han Ji Sun Kim Byung Geun Cho Jin Han Nam Kyung Jin |
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| Affiliation: | Sang Ock Kim,Sang Young Han,Yang Hyun Baek,Sung Wook Lee,Ji Sun Han,Byung Geun Kim,Jin Han Cho,Kyung Jin Nam Department of Gastroenterology and Hepatology,Dong-A University Hospital,Dongdaesin-dong,Seo-gu,Busan 602-103,South Korea Liver Center,Dong-A University College of Medicine,3-ga,Dongdaesing-dong,South Korea Department of Radiology,South Korea |
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| Abstract: | ![]()
Sorafenib,a multitargeted tyrosine kinase inhibitor,has been shown to improve survival in patients with advanced hepatocellular carcinoma(HCC).As the clinical use of sorafenib increases,many adverse effects have been reported,such as hand-foot skin reaction,diarrhea,anorexia,asthenia,alopecia,weight loss,hypertension and arterial thromboembolism.However,there are no prior reports of splenic infarction as an adverse effect of sorafenib.Here,a case of splenic infarction in a patient with HCC who was treated w... |
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| Keywords: | Hepatocellular carcinoma Sorafenib Tyrosine kinase inhibitor Adverse effects Splenic infarction |
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