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葱子化学成分的研究(Ⅱ)
引用本文:原源,来威,杨琦,孙连娜,陈万生.葱子化学成分的研究(Ⅱ)[J].药学实践杂志,2010,28(6):426-428.
作者姓名:原源  来威  杨琦  孙连娜  陈万生
作者单位:1. 解放军第85医院药剂科,上海,200052
2. 第二军医大学药学院,上海,200433;第二军医大学附属长征医院药学部,上海,200003
3. 第二军医大学附属长征医院药学部,上海,200003
4. 第二军医大学药学院,上海,200433
基金项目:国家自然科学基金(30873154)
摘    要:目的研究百合科葱属植物葱Allium fistulosum L.的干燥成熟种子的化学成分。方法采用多种柱色谱方法进行分离纯化,通过理化常数和1H-NMR、13C-NMR、ESI-MS等波谱技术进行化合物的结构鉴定。结果从葱子水提取物的50%乙醇大孔树脂洗脱部位中分离得到了6个化合物,分别鉴定为,壬二酸(Ⅰ),阿魏酸(Ⅱ),香草酸(Ⅲ),对羟基苯甲酸甲酯(Ⅳ),(R)-(+)-2-羟基-3-苯基丙酸(Ⅴ),对羟基苯甲酸(Ⅵ)。结论以上化合物均为首次从葱子中分离得到。

关 键 词:葱子  化学成分
收稿时间:6/7/2010 12:00:00 AM
修稿时间:2010/7/17 0:00:00

Study on chemical constituents of Semen Allii Fistulosi
YUAN Yuan,LAI Wei,YANG Qi,SUN Lian-na and CHEN Wan-sheng.Study on chemical constituents of Semen Allii Fistulosi[J].The Journal of Pharmaceutical Practice,2010,28(6):426-428.
Authors:YUAN Yuan  LAI Wei  YANG Qi  SUN Lian-na and CHEN Wan-sheng
Institution:Department of Pharmacy,No.85th Hospital of PLA,Shanghai 200052,China;School of Pharmacy,Second Military Medical University,Shanghai 200433,China;Department of Pharmacy,Changzheng Hospital,Second Military Medical University,Shanghai 200003,China;Department of Pharmacy,Changzheng Hospital,Second Military Medical University,Shanghai 200003,China;School of Pharmacy,Second Military Medical University,Shanghai 200433,China;Department of Pharmacy,Changzheng Hospital,Second Military Medical University,Shanghai 200003,China
Abstract:Objective To study the chemical constituents of Semen Allii Fistulosi.Methods The constituents were isolated and purificated by column chromatography.The structures of the constituents were elucidated by spectral and chemical Methods.Results Six compounds were obtained from the water extract of Semen Allii Fistulosi.Structures of compounds were determined as azelaic acid(I),ferulic acid(II),vanillic acid(III),2-methoxyhy droquinone(IV),(R)-(+)-2-hydroxy-3-phenylpropanoic acid(V) and 4-hydroxybenzoic acid(VI).Conclusion All the compounds were isolated from Semen Allii Fistulosi for the first time.
Keywords:Semen Allii Fistulosi  chemical constituents
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