妊娠期糖尿病早期干预的临床治疗探讨

目的探讨通过妊娠期糖尿病（GDM）的早期干预措施对降低GDM母儿并发症的影响。方法对2003年7月～2006年6月该院进行产前检查并分娩的孕前健康、无合并症的1823例孕妇资料进行回顾性分析，将不同孕周筛查出的GDM分为3组（早期干预组、中期干预组和晚期干预组）进行母儿并发症发生的情况进行比较。结果GDM的发病率为6．1％，糖耐量异常的发病率为3．9％，未经干预而糖耐量异常最终发展为GDM者为9．7％。早期及中期干预组较晚期干预组GDM母儿并发症发生率明显降低，两者比较差异存在显著性（P〈0．05）。晚期干预组应用胰岛素治疗的孕妇较早期及中期干预组明显增加，两者之间差异存在显著性（P〈0．05）。结论对诊断明确的GDM患者尽早进行干预可降低妊娠期糖尿病并发症的发生率及新生儿患病率。减少胰岛素的使用率。

Early management of gestational diabetes mellitus

Objectives To explore the effect on early management of gestationnal diabetes mellitus(GDM)and perinatal outcome.Methods Retrospectively analysed the 1823 cases of gestational women,and furtherly divided the gestational women with GDM into three groups according to the gestational phases,namely early management group,moderate management group and advanced management qroup.Results The morbidity rate of GDM and IGT are 6.1% and 3.9% respectively.The morbidity rates of GDM complications with early and moderate management are strikingly lower than the advanced management group(P <0.05).The use of insulin in the advanced management of GDM is distinguishedly more than that in the early and moderate management group(P <0.05).Conclusion The early management to GDM can decrease the morbidity rate of complications of GDM and the new-born sickness rate.