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| 荧光定量PCR检测梅毒孕妇引产胎盘脐带组织中的梅毒螺旋体 | |
| 引用本文： | 彭石潜,张荣,黄志明,洪福昌,熊礼宽,周华. 荧光定量PCR检测梅毒孕妇引产胎盘脐带组织中的梅毒螺旋体[J]. 岭南皮肤性病科杂志, 2004, 11(3): 221-223 |
| 作者姓名： | 彭石潜 张荣 黄志明 洪福昌 熊礼宽 周华 |
| 作者单位： | 1. 广东省深圳市宝安区慢性病防治院,广东,深圳,518133 2. 广东省深圳市慢性病防治院,广东,深圳,518010 |
| 摘 要： | 目的：研究荧光定量PCR(FQ-PCR)检测梅毒孕妇引产胎盘脐带组织中的梅毒螺旋体，评估其在早期诊断先天梅毒中的作用。方法：采用荧光定量PCR技术检测13例梅毒孕妇引产胎盘脐带组织中的梅毒螺旋体DNA。结果：13例胎盘和脐带标本中6例(46．15％)荧光定量PCR检测阳性，6例阳性者中，4例未接受治疗，2例接受了治疗。结论：FQ-PCR可检出胎盘脐带组织中的梅毒螺旋体，可用于先天梅毒的早期诊断，干预治疗并不能完全阻断妊娠期间梅毒螺旋体的垂直传播。 |
| 关 键 词： | 脐带 梅毒螺旋体 引产 胎盘 治疗 荧光定量PCR检测 孕妇 标本 先天梅毒 |
| 文章编号： | 1009-8968(2004)03-0221-03 |
| 修稿时间： | 2004-05-20 |
Detection of Treponema pallidum DNA in the Placentas of Induced Labor in Syphilis with Pregnanay |
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| PENG Shi-qian,ZHANG Rong,HUANG Zhi-ming,HONG Fu-chang,Xiong Li-kuan,ZHOU Hua. Detection of Treponema pallidum DNA in the Placentas of Induced Labor in Syphilis with Pregnanay[J]. Southern China Journal of Dermato-Venereology, 2004, 11(3): 221-223 | |
| Authors: | PENG Shi-qian ZHANG Rong HUANG Zhi-ming HONG Fu-chang Xiong Li-kuan ZHOU Hua |
| Abstract: | Objective:To evaluate the FQ-PCR detection of Treponema pallidum DNA in syphilis with pregnancy for the early diagnosis of congenital syphilis. Methods:The Treponema pallidum DNA in 13 placentas of induced labor were detected by FQ-PCR amplification and results were analysed. Results:Treponema pallidum DNA were positive in 6(46.5%) out of the 13 placentas. Among those 6 positive, two had received treatment of recommended regimens and the other fours were not. Conclusion:It was concluded that detection of Treponema pallidum DNA by FQ-PCR might be one of the useful method in the diagnosis of early congenial syphilis. The study results indicated that the syphilis transmission to fetus through placentas may happen during the pregnancy both with and without effective treatment.[ |
| Keywords: | Treponema pallidum Placentas FQ-PCR congenital syphilis |
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