Conventional nutritional counselling maintains nutritional status of patients on continuous ambulatory peritoneal dialysis in spite of systemic inflammation and decrease of residual renal function |
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Authors: | FABIOLA MARTÍ N-DEL-CAMPO,LILIANA GONZÁ LEZ-ESPINOZA,ENRIQUE ROJAS-CAMPOS,NORMA RUIZ,JUANA GONZÁ LEZ,LEONARDO PAZARÍ N, ALFONSO M CUETO-MANZANO |
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Affiliation: | Unit of Medical Research in Renal Diseases, Hospital de Especialidades, CMNO,;Nephrology Department, Hospital General Regional No. 46,;Nephrology Department, Hospital General Regional No. 110, and;Internal Medicine Department, Hospital General de Zona No. 14, IMSS, Guadalajara, Mexico |
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Abstract: | Aim: To evaluate the effect of nutritional counselling on nutritional status in peritoneal dialysis patients. Methods: Twenty‐nine peritoneal dialysis patients were randomly selected to receive conventional nutritional counselling during 6 months of follow up. All patients had monthly clinical and biochemical evaluations, and assessments of dialysis adequacy, inflammation and nutritional status at 0, 3 and 6 months. Results: Moderate‐severe malnutrition decreased 28% whereas normal nutrition increased 23% at final evaluation (non‐significant). Calorie and protein intake remained stable throughout the study (baseline vs final, calorie: 24 ± 8 vs 23 ± 5 Kcal/kg; protein: 1.1 ± 0.5 vs 1.0 ± 0.3 g/Kg, respectively). On the other hand, triceps (16 ± 6 vs 18 ± 8 mm) and subscapular (17 ± 8 vs 20 ± 5 mm) skinfold thicknesses, and mid‐arm circumference (27 ± 3 vs 28 ± 3 mm) significantly increased; mid‐arm muscle area displayed a non‐significant trend to increase (30 ± 9 vs 31 ± 9 cm2) whereas serum albumin significantly increased at the end of study (2.67 ± 0.46 vs 2.94 ± 0.48 g/dL). At final evaluation, median renal creatinine clearance decreased (6.3 (0.8–15.3) vs 2.0 (0.1–6.3) L/week per 1.73 m2) whereas interleukin‐6 increased (2.33 (1.9–7.0) vs 4.02 (2.1–8.4) pg/mL). Conclusion: Even though conventional nutritional counselling, as an isolated measure, did not significantly improve all nutritional parameters, it prevented a greater deterioration during 6 months. Nutritional counselling maintained the nutritional status in spite of a decrease in residual renal function and higher systemic inflammation. |
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Keywords: | continuous ambulatory peritoneal dialysis inflammation nutritional counselling protein-calorie malnutrition residual renal function |
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