| Inhibitiory Effect of Scoparone on Inflammatory Mediator of Asthmatic Models of Guinea Pigs |
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| 作者姓名： | Mei - mi Zhao Zan Teng Zhi Li Hong - rui Liu Jin - sheng Zhao Xiu - hua Yu Ying Fan Yasuo Watanabe |
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| 作者单位： | [1]Department of Ethnopharmacology, China Medical University; Shenyang 110001, China [2]Department of Pharmacology/Pharmacotherapy Nihon PharmaceuticalUniversity 10281 Komuro, Ina - machi, Kita - Adachi - gun, Saitama 362 - 0806 |
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| 摘 要： | Aim Bronchial asthma is a chronic inflammatory disease of the airways, is characterized by massive infiltration of eosinophils and airway hyperreactivity （ AHR）, which are caused by overproduction of inflammatory factors. It was reported that Scoparone possessed anti-inflammation and calcium antagonistic effects. We found that the dilatory effect of scoparone on the tracheal smooth muscle of guinea-pig, hence we presumed that scoporone might cure bronchial asthma. There has not been any report about anti-inflammation activity of scoparone on asthma, so we investigated the anti -inflammation activity of scoparone via using asthmatic models of guinea pig.
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| 关 键 词： | 炎症 支气管哮喘 动物实验 几内亚猪 |
Inhibitiory Effect of Scoparone on Inflammatory Mediator of Asthmatic Models of Guinea Pigs |
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| Authors: | Mei;-;mi;Zhao;Zan;Teng;Zhi;Li;Hong;-;rui;Liu;Jin;-;sheng;Zhao;Xiu;-;hua;Yu;Ying;Fan;Yasuo;Watanabe |
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