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Concentrations of dopamine and noradrenaline in some limbic and related regions of the human brain
Authors:P. Nyberg,R. Adolfsson,N.-E. Andé  n,B. Winblad
Affiliation:Departments of Pathology, University of Uppsala, Sweden;Psychiatry, University of Umeå, University of Uppsala, Sweden;Department of Medical Pharmacology, University of Uppsala, Sweden
Abstract:
The concentrations of dopamine and noradrenaline were determined in some limbic, cortical, striatal and mesencephalic regions of 12 humans. The highest concentrations of dopamine were found in the neostriatum and in the nucleus accumbens. Lower but significant values were detected in the globus pallidus, the substantia perforata anterior, the substantia nigra and in the region medial to the substantia nigra (area A 10). The concentrations of noradrenaline were generally low with the highest values in the area A 10 and the substantia perforata anterior.
Keywords:Dopamine    noradrenaline    limbic system    corpus striatum    mesencephalon
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