干部体检中脂肪肝的患病情况及相关因数分析

目的 分析干部群体中脂肪肝的惠病情况，探讨其发病的相关因素。方法 对参加健康体检的534名机关干部，做血脂、血糖及血尿酸等生化检查，同时做腹部B超、心电图和胸片等检查，并将检查资料录入微机，对脂肪肝组和非脂肪肝组进行对比分析。结果 脂肪肝的检出率为23．6％，男性明显高于女性，约是女性的2．5倍（P〈0．01）：脂肪肝检出率青年、中年和老年组间无统计学差异（P〉0．05）；脂肪肝组的体重指数（BMI）、血甘油三酯（TG）、血高密度脂蛋白胆固醇（HDL-C）、空腹血糖（FBG）、餐后2h血糖（PBG2h）和血尿酸（UA）水平与非脂肪肝组比较差异有显著性（P〈0．01）；脂肪肝组中并存肥胖症、血脂异常、高血压、糖耐量低减、糖尿病和高尿酸血症的发生率显著高于非脂肪肝组（P〈0．01）。结论 脂肪肝的发病与性别密切相关．肥胖、糖尿病、以高TG血症和低HDL-C血症为主的血脂异常是其发病的重要因素；控制体重、纠正血脂异常和降低糖尿病患者的血糖是防治脂肪肝的重要措施。

Analysis of the status of fatty liver and related factors in health examination of ocadre

Objective] To analyse the status of fatty liver and to explore the related factors of fatty liver in cadres.Methods] 534 cases of officials who came to take part in the healthy examination,received measurement of the level of blood lipids,glucose and uric acid,at the same time,to inspect type B ultrasonic waves examination of liver and kidney after measuring electrocardiogram(ECG),chest-X-ray.The populations with fatty liver were compared with those without fatty liver.Results] The ratio of fatty liver among the officials is about 23.6%,the male's ratio is higher than the female's,it's about 2.5 times of the female's(P <0.01).There was no significant difference in incidence of fatty liver among the young groups,middle ages' and the old groups(P >0.05);but there was significant difference between the fatty liver and the non-fatty liver groups of their body mass index(BMI),the lever of blood triglyceride(TG),high density lipoprotein-cholesterol(HDL-C),fasting blood glucose(FBG),2-hour postprandial blood glucose(PBG2h)and uric acid(UA)(P <0.01);The ratios of obesity,dyslipidemia,hypertension,impaired glucose tolerance(IGT),diabetes mellitus(DM),hyperuricemia in fatty liver group were significantly higher than non-fatty liver group(P <0.01).Conclusions] Fatty liver is associated with sex.Obesity,DM,dyslipidemia which is especial for hypertriglyceridemia and low HDL-C are important factors of fatty liver;To control the body weigh,redress the abnormality of blood lipid,reduce the BG of the DM are the most important measures to prevent and cure the fatty liver.