2014年广西肿瘤登记地区结直肠肛门癌发病和死亡分析

目的  分析2014年广西结直肠肛门癌发病和死亡情况。方法  按照全国肿瘤登记中心制定的审核方法和评价标准评估广西肿瘤登记地区上报的2014年肿瘤登记数据，将9个入选的肿瘤登记地区的肿瘤发病、死亡和人口数据进行汇总，按地区（城乡）、性别、年龄别分层，计算结直肠肛门癌的发病率、死亡率、构成比和截缩率等。人口标准化率根据2000年全国人口普查结构和Segis′s世界人口结构。结果  2014年广西纳入分析的9个肿瘤登记地区结直肠肛门癌新发病例为1 716例（其中男性1 039例，女性677例），发病率为24.74/10万，中标率为19.68 /10万，世标率为19.37/10万，男性发病率高于女性（28.73% vs 20.40%，χ²=48.433，P<0.001）；城市地区发病率为36.19/10万，中标率为27.45/10万；农村地区发病率为19.24/10万，中标率为16.07/10万。结直肠肛门癌死亡病例827例（其中男性518例，女性309例），死亡率为11.93/10万，中标率为9.06/10万，世标率为9.00 /10万，男性死亡率高于女性（14.32% vs 9.31%，χ²=36.400，P<0.001）；城市地区死亡率为17.63/10万，中标率为13.21/10万；农村地区死亡率为9.18/10万，中标率为7.13/10万。结论  广西肿瘤登记地区结直肠肛门癌发病和死亡例数男性均高于女性，城市地区高于农村地区，45岁以上的中老年人群尤其是城市地区男性人群是重点开展肿瘤防治工作的对象。

Incidence and mortality of colorectal cancer in areas with cancer registration in Guangxi,2014

Objective  To analyze the incidence and mortality of colorectal cancer in Guangxi in 2014 based on areas with cancer registry reporting. Methods A total of 11 cancer registries of Guangxi reported cancer data for 2014，and 9 registries were found to conform to data quality criteria of the National Central Cancer Registry（NCCR）. Data from these 9 registries were analyzed to determine incidence and mortality of colorectal cancer stratified by areas（urban/rural），sex，and age group，and cumulative incidence/mortality rates，proportions，and truncated incidence/mortality rates were calculated. The Chinese population census in 2000 and Segi′s population were used for age-standardized incidence/mortality rates. Results  The  number of new colorectal cancer cases was 1，716（males 1，039，females 677） from 9 registry areas. The crude incidence of colorectal cancer in Guangxi cancer registration areas was 24.74/105，age-standardized incidence rates was 19.68/105 based on the Chinese standard population（ASR China）and 19.37/105 based on the world standard population（ASR world），and the colorectal cancer incidence rate of males was significantly higher than females（28.73%  vs 20.40%，χ²=48.33，P<0.001）. The incidence of colorectal cancer and ASR China were 36.19/105 and 27.45/105 in urban areas，compared to 19.24/105 and 16.07/105 in rural areas. The total number of colorectal cancer-related deaths was 827（males 518，females 309）. Crude mortality associated with colorectal cancer in Guangxi cancer registration areas was 11.93/105， age-standardized mortality rate was 9.06/105 based on the Chinese standard population（ASR China）and 9.00/105 based on the world standard population （ASR world），and the colorectal cancer mortality rate of males was significantly higher than females（14.32%  vs 9.31%，χ²=36.400，P<0.001）. Mortality associated with colorectal cancer and ASR China were 17.63/105 and 13.21/105 in urban areas，compared to 9.18/105 and 7.13/105 in rural areas. Conclusions In Guangxi，incidence of colorectal cancer and associated mortality are obviously higher in males than in females. The incidence and mortality of colorectal cancer are higher in urban areas than in rural areas.Urban male over 45 years old is the the main target population for cancer prevention and treatment.