惠州市2013—2017年无偿献血者HIV检测结果

目的 调查惠州市无偿献血者HIV感染情况、为后续的献血者招募及HIV防治提供数据支持。方法 收集惠州市2013年1月1日—2017年12月31日5年期间无偿献血者的HIV检测资料,并进行统计学分析。结果 惠州市2013—2017年共检测无偿献血者标本326 388份,HIV抗体筛查阳性待确证标本187例,其中HIV抗体确证结果阳性138例,确证阳性率为4.22/万,核酸检测阳性结果与确证结果符合率为99.28%;HIV抗体确证结果阴性33例,核酸阴性结果与确证结果符合率为100.00%;HIV抗体确证结果不确定者16例,占8.56%,其中核酸检测结果有反应者2例,4周后随访,HIV抗体确证结果转为阳性;男性平均确证阳性率为5.13/万,女性为1.48/万。26~35岁年龄段的确证阳性率最高,最低确证阳性率的年龄段为46~60岁。结论 对HIV抗体不确定结果人群应结合核酸和抗体确证的结果进行综合判定;加强献血前健康征询工作,将HIV感染者隔离于献血前,从而从源头上保障血液安全;5年间惠州市无偿献血普通人群HIV感染率一直处于稳定的低流行状态。

Results of HIV detection among voluntary blood donors in Huizhou, 2013-2017

Objective To investigate the epidemiological characteristics of HIV infection among voluntary blood donors in Huizhou City, so as to provide the data support for subsequent recruitment of voluntary blood donors and the prevention and treatment of HIV infection. Methods The data of voluntary blood donors with HIV infection in Huizhou City from 2013 to 2017 were collected and analyzed statistically. Results Totally 326 388 samples of voluntary blood donors were collected and detected. Totally 187 donors were HIV reactive and 138 of which were determined positive in the WB test. The positive rate of confirmatory test was 4.22/10⁵, and the coincidence rate of the positive results of nucleic acid detection and confirmation was 99.28%. A total of 33 samples were confirmed negative by WB and these samples were tested to be HIV RNA non-reactive. Totally 16 samples(8.56%) were found the indeterminate-result by WB, but 2 cases of which were tested to be HIV RNA reactive and HIV antibody was confirmed to be positive by WB after 4 weeks. The average confirming positive rate of male was 5.13/10⁵ and female was 1.48/10⁵. The positive rate of confirmation in the 26~35 age group is the highest, and the positive rate in the 46~60 age group is the lowest. Conclusion sIt is a good way to solve the uncertain results by comprehensively determining the results of HIV RNA and WB. There is a stable low prevalence of HIV infection rate of the general population in Huizhou City in recent 5 years.