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| 舒心和饮对大鼠心肌缺血再灌注损伤的保护作用 | |
| 引用本文： | 马中建,李花,康文萍. 舒心和饮对大鼠心肌缺血再灌注损伤的保护作用[J]. 中医药导报, 2008, 14(3): 9-11 |
| 作者姓名： | 马中建 李花 康文萍 |
| 作者单位： | 1. 衡东县中医院,湖南,衡东,421400 2. 湖南中医药大学,湖南,长沙,410007 3. 衡东县人民医院,湖南,衡东,421400 |
| 摘 要： | 目的:研究舒心和饮对健康成年SD大鼠心肌缺血再灌注损伤的保护作用。方法:SD大鼠以结扎左冠状动脉30min,再通30 min造成心肌缺血再灌注损伤模型,通过观察心电图、心肌酶学指标,评价舒心和饮对心肌的保护作用。结果:舒心和饮可有效改善心脏缺血再灌注心电图病理改变,降低缺血再灌注后血中乳酸脱氢酶和肌酸激酶活性,表明舒心和饮能明显减轻心肌组织的损伤。结论:舒心和饮对大鼠心肌缺血再灌注损伤有保护作用。 |
| 关 键 词： | 舒心和饮 缺血再灌注 乳酸脱氢酶 肌酸激酶 心电图 |
| 文章编号： | 1672-951X(2008)03-0009-02 |
| 修稿时间： | 2007-12-12 |
Protective Effects of Shuxinheyin on Myocardium Ischemia-reperfusion Injury in Rats |
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| MA Zhong-jian,LI Hua,KANG Wen-pin. Protective Effects of Shuxinheyin on Myocardium Ischemia-reperfusion Injury in Rats[J]. GUIDING JOURNAL OF TCM, 2008, 14(3): 9-11 | |
| Authors: | MA Zhong-jian LI Hua KANG Wen-pin |
| Abstract: | Objective: To investigate the protective effects of Shuxinheyin on myocardial ischemia-reperfusion injury in adult SD rats.Methods:The myocardial injury of rats induced by ischemia reperfusion was produced by the ligation of left coronary artery for 30 min followed by 30 min reperfusion.The effects were evaluated based on changes of ST segment in an electrocardiogram(ECG) and levels of serum creatine kinase(CK) and lactatede hydrogenase(LDH).Results: Compared with the model rats,the up-slop of ST segments was slow down in the low and high dosed groups(P<0.05).The levels of serum creatine kinase and lactatede hydrogenase declined(P<0.05).Conclusion: Shuxinheyin can protect rats' myocardial tissues from myocardial ischemia-reperfusion injury. |
| Keywords: | Shuxinheyin Ischemia-reperfusion Lactatede hydrogenase(LDH) Creatine kinase(CK) Electrocardiogram(ECG) |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |