孕妇HBsAg携带状态与产后首次喂养行为选择的关系

 目的 探讨孕妇乙肝感染对产后首次喂养行为的影响。方法 采用前瞻性研究,招募2014年1月1日至2015年1月31日到安庆市立医院就诊的住院孕妇,通过调查问卷及医院住院孕妇电子病历信息系统收集孕妇的基本信息,收集血清进行乙肝表面抗原(HBV surface antigen,HBsAg)检测,产后1周时电话随访活产分娩孕妇,获取首次喂养行为信息,并通过单因素和多因素统计方法分析乙肝感染与首次喂养行为的关联。结果 共纳入1 826名孕妇。安庆市孕妇人群产后首次喂养以纯母乳方式为主(77.7%,1418/1826);HBeAg(+)/HBsAg(+)、HBeAg(-)/HBsAg(+)及HBsAg(-)3组孕妇产后首次喂养选择纯母乳方式的比例分别为70.8%(17/24),75.8%(91/120)和77.9%(1310/1682),差异无统计学意义。结论 安庆市孕妇人群分娩后首次喂养方式中,母乳喂养比例较高,未发现HBV的携带状态影响孕妇产后首次喂养行为的选择。

The relationship between maternal HBsAg state and initiate feeding behavior in pregnant women

Objective  To investigate the effect of hepatitis B virus infection on initiate feeding behavior of pregnant women in Anqing city.Methods  A prospective study was conducted among pregnant women who were recruited from Jan.1,2014 to Jan.31,2015 in Anqing City hospital.The base-line information was collected by using the questionnaire and the electronic medical record   information system.Serum samples were also collected for HBV surface antigen (HBsAg) test.Pregnant women who had live fetus were selected to follow up by using telephone and information about initiate feeding behavior was obtained.The single variate and multivariate analysis were used to compare the initiate feeding behavior by the HBV status.Results  A total of 1 826 pregnant women were enrolled.Breastfeeding was the main choice (77.7%,1 418/1 826) after delivery.The initiate breastfeeding rate of HBeAg (+) /HBsAg (+),HBeAg (+) /HBsAg (+) and HBsAg (-) group was 70.8%(17/24),75.8%(91/120)and 77.9%(1 310/1 682),respectively.The difference among three groups was not statistically significant.Conclusions  Our results suggested that the initiate breastfeeding rate is high among pregnant women in Anqing city, and maternal HBV state did not have an obvious correlation with the initiate feeding ways.