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乌司他丁联合血必净注射液治疗有机磷农药中毒疗效观察
引用本文:卢茂林,周晓光,郝鸿斌. 乌司他丁联合血必净注射液治疗有机磷农药中毒疗效观察[J]. 现代中西医结合杂志, 2011, 20(11): 1311-1313,1316
作者姓名:卢茂林  周晓光  郝鸿斌
作者单位:安徽省泗县人民医院,安徽,泗县,234300
摘    要:目的观察乌司他丁联合血必净注射液治疗急性重度有机磷农药中毒的疗效。方法将58例急性重度有机磷农药中毒患者随机分为2组:对照组29例给予反复洗胃,长托宁和胆碱酯酶复能剂等常规治疗,实验组29例在对照组基础上加用乌司他丁联合血必净注射液治疗,对比观察2组治愈率、治愈时间和中毒后心、肝、肾重要脏器损害发生率。结果实验组和对照组之间治愈率存在显著性差异(93%vs 66%,P<0.01)。实验组和对照组之间治愈时间有显著性差异((8.8±4.7)d vs(17.2±5.3)d,P<0.01)。实验组全血胆碱酯酶及肌酸激酶同工酶的恢复优于对照组(P<0.01或0.05)。实验组血气的改善优于对照组(P<0.01)。治疗5 d后2,组CRP均明显下降,均有显著性差异(P均<0.01);且实验组下降更显著(P<0.01)。结论常规治疗基础上加用乌司他丁联合血必净注射液治疗急性重度有机磷中毒能缩短患者住院时间,提高治愈率,保护重要脏器功能。

关 键 词:有机磷农药中毒  乌司他丁  血必净注射液  长托宁

Curative effect observation of ulinastatin combined with Xuebijing injection on organophosphorus pesticide poisoning
Lu Maolin,Zhou Xiaoguang,Hao Hongbin. Curative effect observation of ulinastatin combined with Xuebijing injection on organophosphorus pesticide poisoning[J]. Modern Journal of Integrated Chinese Traditional and Western Medicine, 2011, 20(11): 1311-1313,1316
Authors:Lu Maolin  Zhou Xiaoguang  Hao Hongbin
Affiliation:Lu Maolin,Zhou Xiaoguang,Hao Hongbin(The People's Hospital of Si County,Si County 234300,Anhui,China)
Abstract:Objective It is to observe the curative effect of ulinastatin combined with Xuebijing injection on acute severe organophosphorus pesticide poisoning.Methods 58 patients with acute severe organophosphorus pesticide poisoning were randomly divided into two groups.29 cases were in control group and treated with repeatedly gastric lavage and routine therapy included Changtuoning and cholinesterase reactivator.The other 29 cases were in experimental group and treated with ulinastatin combined with Xuebijing inje...
Keywords:organophosphorus pesticide poisoning  ulinastatin  Xuebijing injection  Changtuoning  
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