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| 益气安痫胶囊抗癫痫作用的实验研究 | |
| 引用本文： | 李国风,李兰芳,张建新,张勤增,解丽君,郝娜,王薇,李立萍. 益气安痫胶囊抗癫痫作用的实验研究[J]. 现代中西医结合杂志, 2011, 20(10): 1189-1190 |
| 作者姓名： | 李国风 李兰芳 张建新 张勤增 解丽君 郝娜 王薇 李立萍 |
| 作者单位： | 河北省医学科学院药物研究所,河北,石家庄050021 |
| 摘 要： | 目的观察益气安痫胶囊的抗癫痫作用。方法采用最大电休克法和士的宁致惊厥法,观察益气安痫胶囊对小鼠发生惊厥的潜伏期、惊厥小鼠数和惊厥后死亡小鼠数的影响;采用戊巴比妥钠小鼠睡眠法,观察益气安痫胶囊对小鼠睡眠潜伏期、睡眠持续时间的影响。结果益气安痫胶囊有抗最大电休克作用,可降低电刺激致小鼠惊厥率及士的宁致小鼠惊厥率和病死率,延长士的宁致小鼠惊厥和死亡的潜伏期,缩短阈剂量戊巴比妥钠致小鼠的睡眠潜伏期和延长小鼠睡眠时间。结论益气安痫胶囊具有明显抗癫痫作用。 |
| 关 键 词： | 抗癫痫 抗惊厥 益气安痫胶囊 |
Experimental study of anti-effect of Yiqianxian capsule on epilepsy |
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| Li Guofeng,Li Lanfang,Zhang Jianxin,Zhang Qinzeng,Xie Lijun,Hao Na,Wang Wei,Li Liping. Experimental study of anti-effect of Yiqianxian capsule on epilepsy[J]. Modern Journal of Integrated Chinese Traditional and Western Medicine, 2011, 20(10): 1189-1190 | |
| Authors: | Li Guofeng Li Lanfang Zhang Jianxin Zhang Qinzeng Xie Lijun Hao Na Wang Wei Li Liping |
| Affiliation: | Li Guofeng,Li Lanfang,Zhang Jianxin,Zhang Qinzeng,Xie Lijun,Hao Na,Wang Wei,Li Liping(Institute of Pharmaceutical Research,Hebei Province Academy of Medical Science,Shijiazhuang 050021,Hebei,China) |
| Abstract: | Objective It is to observe the anti-effect of Yiqianxian capsule(YAC) on epilepsy.Methods The effects of YAC on the eclampsia delitescence,the number of the eclamptic mice and the number of the dead mice after eclampsia in the mice eclampsia models set up by electric stimulation and ip Strychnine were observed.The effect of YAC on the sleeping delitescence and the sleeping persistence time in the mice sleeping model set up by ip Pentobarbital were observed.Results YAC had anti-maximal electroshock role,and ... |
| Keywords: | anti-epileptic Yiqianxian capsule anti-eclampsia |
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