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当归、红芪超滤膜提取物对急性心肌缺血大鼠CK及CK-MB的影响
引用本文:李子佳,李应东,赵信科,刘凯. 当归、红芪超滤膜提取物对急性心肌缺血大鼠CK及CK-MB的影响[J]. 现代中西医结合杂志, 2011, 20(8): 933-934
作者姓名:李子佳  李应东  赵信科  刘凯
作者单位:甘肃中医学院,甘肃,兰州,730000
摘    要:目的观察当归、红芪超滤膜提取物对急性心肌缺血大鼠肌酸激酶(CK)及肌酸激酶同工酶(CK-MB)的影响。方法以冠状动脉左前降支结扎法结扎80只大鼠制作急性心肌梗死模型。造模成功后,随机分为1 d、3 d、7 d、14 d组,每组20只;对动物进行用药后在对应的时间点将动物处死取血。用全自动生化仪测定血清CK及CK-MB含量。结果血清CK及CK-MB含量在不同药物组大鼠之间有显著性差异(P均<0.05)。结论当归、红芪超滤膜提取物能降低急性心肌缺血大鼠血清CK及CK-MB活性,且与用药时间及剂量密切相关。

关 键 词:当归  红芪  超滤膜  急性心肌缺血

Influence of Danggui and Hongqi ultrafiltration membrane extract on CK and CK-MB in acute myocardial ischemia rat
Li Zijia,Li Yingdong,Zhao Xinke,Liu Kai. Influence of Danggui and Hongqi ultrafiltration membrane extract on CK and CK-MB in acute myocardial ischemia rat[J]. Modern Journal of Integrated Chinese Traditional and Western Medicine, 2011, 20(8): 933-934
Authors:Li Zijia  Li Yingdong  Zhao Xinke  Liu Kai
Affiliation:Li Zijia,Li Yingdong,Zhao Xinke,Liu Kai(Gansu Traditional Chinese Medical College,Lanzhou 730000,Gansu,China)
Abstract:Objective It is to observe the influence of Danggui and Hongqi ultrafiltration membrane extract on creatine kinase(CK) and creatine kinase isoenzyme(CK-MB) in acute myocardial ischemia rat.Methods 80 rats were given left anterior descending coronary artery ligation to establish acute myocardial infarction model.After the model established,80 rats were randomly divided into 1 d group,3 d group,7 d group and 14 d group in which there were 20 rats.After treatment,the animals were killed at the corresponding ti...
Keywords:Danggui  Hongqi  ultrafiltration membrane  acute myocardial ischemia  
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