Epstein–Barr virus encephalitis in a renal transplant recipient manifesting as hemorrhagic,ring‐enhancing mass lesions |
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| Authors: | J.M. Babik S. Katrak S. Miller M. Shah P. Chin‐Hong |
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| Affiliation: | 1. Division of Infectious Diseases, Department of Medicine, University of California San Francisco, San Francisco, California, USA;2. Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA;3. Department of Neurology, University of California San Francisco, San Francisco, California, USA |
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| Abstract: | Epstein–Barr virus (EBV) encephalitis has been infrequently described in immunocompromised patients. Here, we report a unique case of biopsy‐proven EBV encephalitis in a renal transplant recipient presenting with altered mental status, prominent visual disturbances, and hemorrhagic, ring‐enhancing mass lesions on magnetic resonance imaging. The patient was successfully treated with a prolonged course of antivirals. This case illustrates the difficulty in interpretation of cerebrospinal fluid EBV polymerase chain reaction assay, given the lack of specificity in immunocompromised patients. |
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| Keywords: | Epstein– Barr virus encephalitis renal transplant immunocompromise primary central nervous system lymphoma post‐transplant lymphoproliferative disorder ganciclovir valganciclovir |
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