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Sensory Ataxic Guillain-Barré Syndrome with Dysgeusia after mRNA COVID-19 Vaccination
Authors:Shunsuke Ogata  Yoshito Ishii  Keiichiro Asano  Erena Kobayashi  Shun Kubota  Keita Takahashi  Yosuke Miyaji  Yuichi Higashiyama  Hideto Joki  Hiroshi Doi  Michiaki Koga  Hideyuki Takeuchi  Fumiaki Tanaka
Affiliation:1.Department of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Japan; 2.Department of Neurology and Clinical Neuroscience, Yamaguchi University Graduate School of Medicine, Japan
Abstract:Guillain-Barré syndrome (GBS) has occasionally occurred in people who have received coronavirus disease 2019 (COVID-19) vaccines. Dysgeusia is rare symptom of GBS. We herein report a rare case of sensory ataxic GBS with dysgeusia just after the second dose of the Pfizer-BioNTech COVID-19 vaccine. Although autoantibodies against glycolipids were not detected, immunotherapy with intravenous immunoglobulin and methylprednisolone pulse therapy effectively ameliorated the symptoms. Our report suggests that the COVID-19 vaccine may induce various clinical subtypes of GBS, including a rare variant with sensory ataxia and dysgeusia.
Keywords:vaccination, COVID-19, Guillain-Barré   syndrome, sensory ataxia, dysgeusia
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