| 围术期桥抗凝治疗的研究现状 |
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| 引用本文： | 赵梦华,石建平,张学强.围术期桥抗凝治疗的研究现状[J].临床急诊杂志,2013(12):613-616. |
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| 作者姓名： | 赵梦华 石建平 张学强 |
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| 作者单位： | 邯郸市中心医院心内科,河北邯郸056001 |
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| 摘 要： | 许多因静脉血栓栓塞症（VTE）、机械性心脏瓣膜或房颤而长期给予华法林抗凝治疗的患者在行重大外科手术或有创性操作时需停用华法林。在围术期以治疗性剂量普通肝素或低分子肝素暂时替代维生素K拮抗剂（VKA）治疗的方法称为桥抗凝治疗。桥抗凝治疗的目的是减少患者暂时停用VKA治疗时发生血栓栓塞事件的风险，但也可能增加患者发生严重出血并发症的风险。此文对围术期桥抗凝治疗的研究现状给予综述。
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| 关 键 词： | 桥抗凝治疗 围术期 肝素 维生素K拮抗剂 |
Current status of perioperative bridging anticoagulation therapy |
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| Abstract: | This article addresses the management of patients who are receiving anticoagulant and require an elective surgery or invasive procedure. Perioperative antithrombotic management strategies is based on risk assessment for thromboembolism and bleeding. In patients requiring vitamin K antagonist （VKA） interruption before surgery,guideline recommend stopping VKA 5 days before surgery. In patients with a mechanical heart valve, atrial fibrillation,or venous thromboembolism at high risk for thromboembolism, suggest bridging anticoagulation;in patients at low risk,suggest no bridging. |
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| Keywords: | bridging anticoagulation therapy perioperative heparin vitamin K antagonist |
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