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SAP signaling: a dual mechanism of action
Authors:Le Borgne Marie  Shaw Andrey S
Affiliation:Department of Pathology and Immunology, Washington University School of Medicine, 660 South Euclid Avenue, Saint Louis, MO 63110, USA.
Abstract:
In this issue of Immunity, Kageyama et?al. (2012), Zhao et?al. (2012), and Dong et?al. (2012) show that the adaptor protein SAP regulates both positive and negative signals through SLAM receptors to stabilize intercellular contacts.
Keywords:
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