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Decline of CSF orexin (hypocretin) levels in Prader–Willi syndrome
Authors:Mayu Omokawa  Tadayuki Ayabe  Toshiro Nagai  Aya Imanishi  Ayumi Omokawa  Seiji Nishino  Yohei Sagawa  Tetsuo Shimizu  Takashi Kanbayashi
Affiliation:1. Department of Neuropsychiatry, Akita University Graduate School of Medicine, Akita, Japan;2. Correspondence to:;3. Mayu Omokawa, M.D., Department of Neuropsychiatry, Akita University Graduate School of Medicine, 1‐1‐1 Hondo, Akita 010‐8543, Japan.;4. E‐mail:;5. Department of Pediatrics, Dokkyo Medical University Koshigaya Hospital, Koshigaya, Japan;6. Department of General Internal Medicine and Clinical Laboratory Medicine, Akita University Graduate School of Medicine, Akita, Japan;7. Sleep and Circadian Neurobiology Laboratory, Stanford University School of Medicine, Palo Alto, California;8. International Institute for Integrative Sleep Medicine (WPI‐IIIS), University of Tsukuba, Tsukuba, Japan
Abstract:
Keywords:Prader–  Willi syndrome  hypersomnia  narcolepsy  orexin  obesity
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