|
|||||
|
|
Biomarkers of pathophysiology in hypertrophic cardiomyopathy: implications for clinical management and prognosis |
|
| Authors: | Cambronero, Francisco Marin, Francisco Roldan, Vanessa Hernandez-Romero, Diana Valdes, Mariano Lip, Gregory Y.H. |
| Affiliation: | 1 Department of Cardiology, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain 2 Centro Regional de Hemodonación, University of Murcia, Spain 3 Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Dudley Road, Birmingham B18 7QH, UK |
| Abstract: | The study of biomarkers and their signalling pathways has allowedthe development of new therapeutic strategies in a range ofdisorders. The aim of the present systematic review is to providean overview of different biomarkers in patients with hypertrophiccardiomyopathy that could give some insight into the pathophysiologicmechanism(s) underlying the typical clinical and histologicalmanifestations of the disease. Several pathophysiological modelsare presented and discussed, including studies that have investigatedthese biomarkers for diagnostic and prognostic reasons, in relationto disease progression and/or mortality. |
| Keywords: | Hypertrophic cardiomyopathy Biomarkers Pathophysiology |
| 本文献已被 Oxford 等数据库收录！ | |