山莨菪碱治疗脑血栓形成的微循环观察

本文报告32例脑血栓形成患者应用山莨菪碱治疗及其前后甲襞及球结膜微循环变化观察。结果:1.32例治疗组应用山莨菪碱治疗总有效率93.75％,对照组总有效率72％(P<0.05)。山莨菪碱治疗后,患者血流速度增快,动、静脉口径比例好转(P<0.01),使临床症状体征好转,收到好的效果。2.观察32例脑血栓形成患者微循环异常率为73.49％。治疗后微循环改变率为83.6％(P<0.01),提示脑血栓形成患者急性期存在脑微循环障碍,应用山莨菪碱治疗能改善微循环障碍。3.通过32例脑血栓形成患者微循环观察,发现观察球结膜比观察甲襞微循环具有更多的信息、更直观,对疾病的诊断、治疗、病情估价更有实用价值。

Microcirculatory Observations on Effect of Anisodaminum on Cerebral Thrombosis Diseases

In this article, 32 cases of cerebral thrombosis were reported. We made an observation on their microcirculation of nailfold and bulbar conjunctiva before and after treated the patients with Anisodaminum (654—Ⅱ). Results: 1. The treatment groups'(32 cases) total efficiency was 93.75％ and the comparable ones'was 72％(P<0.05). The blood flowed faster, the arteriovenous proportion being bigger(P<0.01). thus we could got good results of clinical signs and syptoms. 2. In the 32 cases with cerebral thrombosis, the abnormal rate of the microeirculation was 73.49％, while its improvement one was 83.6％(P<0.01). So we suggest that, at the acute stage, the patients with cerebral thrombosis had disturbance of cerebral mlcrocirculation. 3. By observed the microcirculation of the 32 patients with cerebral thrombosis, we could got more imformation directly from bulbar conjunctiva than nailfold, which was of much practical value to the diagnosis, treatment, evaluation of the disease.