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Chronic recurrent multifocal osteomyelitis and psoriasis—A report of a new association and review of related disorders
Authors:Ronald M. Laxer MDCM   FRCPC   Assistant Professor   Abraham D. Shore MD   FRCPC   Assistant Professor   David Manson MD   Chief Resident   Susan King MD   FRCPC   Fellow   Earl D. Silverman MD   FRCPC   Assistant Professor  Dan M. Wilmot MD   FRCPC   Assistant Professor
Affiliation:Division of Immunology/Rheumatology, Hospital for Sick Children, University of Toronto, Ontario.
Abstract:In summary, we have described two patients with CRMO and psoriasis, and have reviewed the musculoskeletal manifestations associated with pustular eruptions of the palms and soles. In view of the frequent occurrence of PPP in patients with CRMO, we suggest that the occurrence of psoriasis in our two patients is more than coincidence, and that noninfectious, inflammatory lesions of bone may be another musculoskeletal manifestation of psoriasis. This rare association, as well as the association of PPP with disorders associated with new bone formation, may shed new insights on the relatively common finding of periosteal elevation associated with psoriatic arthritis and the occasional severe juxta-articular osteolytic destructive bone lesions seen in psoriatic arthritis.
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