Two new antibacterial norabietane diterpenoids from cyanobacteria, Microcoleous lacustris |
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Authors: | Rosa Martha Pérez Gutiérrez Amalia Martínez Flores Rosario Vargas Solís Javier Carmona Jimenez |
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Affiliation: | (1) Natural Products Research Laboratory, Industrias Extractivas (ESIQUIE)-IPN, Punto Fijo 16, Col. Torres Lindavista, C.P. 07708 Mexico D.F., Mexico;(2) Phytopharmacology Research Laboratory, Universidad Autónoma Metropolitana-Xochimilco, A.P. 23-181 Mexico D.F., Mexico;(3) Ficology Laboratory, Facultad de Ciencias UNAM, C.P. 04510 Mexico D.F., Mexico |
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Abstract: | Two abietane diterpenes were isolated from cyanobacteria Microcoleous lacustris, 20-nor-3α-acetoxyabieta-5,7,9,11,13-pentaene and 20-nor-3α-acetoxy-12-hydroxy-abieta-5,7,9,11,13-pentaene. These compounds were assayed against Staphylococcus aureus, Staphylococcus epidermidis, Salmonella typhi, Vibrio cholerae, Bacillus subtilis, Bacillus cereus, Escherichia coli, and Klebsiella pneumoniae. Both compounds showed activity against S. aureus, S. epidermidis, S. typhi, and V. cholerae, but not against the other bacteria. |
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Keywords: | Cyanobacteria Microcoleous lacustris Abietane diterpenes |
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