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Two new antibacterial norabietane diterpenoids from cyanobacteria, Microcoleous lacustris
Authors:Rosa Martha Pérez Gutiérrez  Amalia Martínez Flores  Rosario Vargas Solís  Javier Carmona Jimenez
Affiliation:(1) Natural Products Research Laboratory, Industrias Extractivas (ESIQUIE)-IPN, Punto Fijo 16, Col. Torres Lindavista, C.P. 07708 Mexico D.F., Mexico;(2) Phytopharmacology Research Laboratory, Universidad Autónoma Metropolitana-Xochimilco, A.P. 23-181 Mexico D.F., Mexico;(3) Ficology Laboratory, Facultad de Ciencias UNAM, C.P. 04510 Mexico D.F., Mexico
Abstract:
Two abietane diterpenes were isolated from cyanobacteria Microcoleous lacustris, 20-nor-3α-acetoxyabieta-5,7,9,11,13-pentaene and 20-nor-3α-acetoxy-12-hydroxy-abieta-5,7,9,11,13-pentaene. These compounds were assayed against Staphylococcus aureus, Staphylococcus epidermidis, Salmonella typhi, Vibrio cholerae, Bacillus subtilis, Bacillus cereus, Escherichia coli, and Klebsiella pneumoniae. Both compounds showed activity against S. aureus, S. epidermidis, S. typhi, and V. cholerae, but not against the other bacteria.
Keywords:Cyanobacteria   Microcoleous lacustris   Abietane diterpenes
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