Improvement of oligoasthenozoospermia in epileptic patients on switching anti-epilepsy medication from sodium valproate to phenytoin |
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| Authors: | Hayashi Tetsuo Yoshida Soichiro Yoshinaga Atushi Ohno Rena Ishii Nobuyuki Yamada Takumi |
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| Affiliation: | Department of Urology, Saitama Medical Center, Saitama Medical School, Kawagoe, Saitama, Japan. |
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| Abstract: | ![]()
We present two cases of infertile male patients with oligoasthenozoospermia who were receiving anti-epilepsy medication. Complete reversal of the spermatic dysfunction followed by a successful conception was achieved after discontinuation of sodium valproate, suggesting that the drug was responsible for spermatic dysfunction in these individuals. |
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