| 基于RAS/RAF/ERK信号通路探讨益气生肌合剂对压力性损伤大鼠创面微小血管生成的作用机制 |
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| 引用本文： | 肖思民,徐凤英,廖若夷.基于RAS/RAF/ERK信号通路探讨益气生肌合剂对压力性损伤大鼠创面微小血管生成的作用机制[J].中国中西医结合外科杂志,2022,28(2):185-190. |
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| 作者姓名： | 肖思民 徐凤英 廖若夷 |
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| 作者单位： | 湖南中医药大学第一附属医院长沙 410208 |
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| 基金项目： | 湖南省科技厅“湖南省临床医疗技术创新引导计划项目”(2017SK50061) |
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| 摘 要： | 目的:观察益气生肌合剂通过调控RAS/RAF/ERK信号通路对压力性损伤大鼠模型创面修复及微小血管生成的影响.方法:32只大鼠分为模型对照组、三乙醇胺乳膏组(阳性药物组)、益气生肌合剂组(益气生肌组)、三乙醇胺乳膏+益气生肌组(联合用药组),每组8只.建立压力性损伤大鼠模型并予不同方式干预.记录各组大鼠创面愈合及病理损...
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| 关 键 词： | 压力性损伤 益气生肌合剂 RAS/RAF/ERK信号通路 微小血管生成 机制研究 |
| 收稿时间： | 2021/9/21 0:00:00 |
Based on RAS/RAF/ERK Signaling Pathway to Explore the Mechanism of YiQi ShengJi Mixture on the Formation of Microangiogenesis in the Wound Surface of a Pressure-Injured Rat Model |
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| XIAO Si-min,XU Feng-ying,LIAO Ruo-yi.Based on RAS/RAF/ERK Signaling Pathway to Explore the Mechanism of YiQi ShengJi Mixture on the Formation of Microangiogenesis in the Wound Surface of a Pressure-Injured Rat Model[J].Chinese Journal of Surgery of Integrated Traditional and Western Medicine,2022,28(2):185-190. |
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| Authors: | XIAO Si-min XU Feng-ying LIAO Ruo-yi |
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| Institution: | The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha 410208, China |
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| Abstract: | |
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| Keywords: | Pressure injury Yiqi Shengji Mixture RAS/RAF/ERK signaling pathway microangiogenesis mechanism research |
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