273例未足月胎膜早破的临床分析

目的探讨未足月胎膜早破(PPROM)发病的诱发因素,不同孕周的分娩方式和妊娠结局。方法回顾研究了2008年1月²012年12月在我院住院分娩的273例未足月胎膜早破的产妇临床资料,探讨疾病诱发因素,并对不同孕周的分娩方式和妊娠结局进行对比分析。结果未足月胎膜早破的发生率为1.57%,生殖道感染为诱发未足月胎膜早破发生的首要因素;孕282012年12月在我院住院分娩的273例未足月胎膜早破的产妇临床资料,探讨疾病诱发因素,并对不同孕周的分娩方式和妊娠结局进行对比分析。结果未足月胎膜早破的发生率为1.57%,生殖道感染为诱发未足月胎膜早破发生的首要因素;孕28³3+6周组与孕3433+6周组与孕34³6+6周组的PPROM分娩方式差异无统计学意义(p>0.05);孕2836+6周组的PPROM分娩方式差异无统计学意义(p>0.05);孕28³3+6周组孕妇的并发症发生率高于孕3433+6周组孕妇的并发症发生率高于孕34³6+6周组,差异有非常显著的统计学意义(p<0.01);孕2836+6周组,差异有非常显著的统计学意义(p<0.01);孕28³3+6周组的新生儿并发症和围产儿死亡率明显高于孕3433+6周组的新生儿并发症和围产儿死亡率明显高于孕34³6+6周组的患者(p<0.05)。结论生殖道感染为未足月胎膜早破的主要诱发因素,针对不同的诱发因素,应采取不同的干预对策,不仅能减少母婴并发症,还降低了围产儿的死亡率。

CLINICAL ANALYSIS OF 273 CASES PRETERM PREMATURE RUPTURE OF MEMBRANES

Objective To explore the inducing factors of preterm premature rupture of membranes and the dehvery way and pregnancy outcome of different gestational age. Methods Review and study the maternal clinical data came from 273 cases of preterm premature rupture of membranes in our hospital from January 2008 to December 2012, explore disease causative factor and comparatively analyze the delivery way and pregnancy outcome of different gestatioual age. Results The incidence of preterm premature rupture of membranes was 1.57%, and it is the prima- ry factor that reproductive tract infections induce the preterm premature rupture of membranes. It has no statistical significant difference （p 〉0. 05） in PPROM between childbirth ways of 28 ~ 33 ＋6 weeks gestation group and 34 - 36 ＋6 weeks gestation group. It has a very significant statistical diference （p 〈 0.01 ） in complications and the inci- dence of complications of group at 28 - 33 ＋6 weeks pregnant which was higher than the group at 34 - 36 ＋6 weeks pregnant. And the neonatal complications and perinatal mortality of group at 28 - 33 ~6 weeks pregnant was signifi- candy higher than the group at 34 ~ 36 ＋6 weeks （p 〈 0. 05 ）. Conclusion The reproductive tract infections is the main inducing factors of preterm premature rupture of membranes, we should take different intervention measures for the different factors, and it not only can reduce the maternal complications but also can reduce the mortality rate of perinatal.