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肾小管上皮细胞凋亡在肾间质纤维化中作用的研究进展
引用本文:杨雅丽,程晓霞. 肾小管上皮细胞凋亡在肾间质纤维化中作用的研究进展[J]. 国际中医中药杂志, 2009, 31(1). DOI: 10.3760/cma.j.issn.1673-4246.2009.01.041
作者姓名:杨雅丽  程晓霞
作者单位:浙江中医药大学第一临床医学院,杭州,310052;浙江省杭州市中医院肾内科,杭州,310007
摘    要:肾小管上皮细胞凋亡是指肾小管受到缺氧、中毒、细胞/炎性反应因子、血浆蛋白或葡萄糖等因素作用后,小管上皮细胞活化、增生,小管扩张、管型形成,最终导致细胞凋亡,小管萎缩或间质纤维化.本文总结了近年来国内外对肾小管上皮细胞凋亡主要机制的探讨及中药对肾间质纤维化的防治研究进展.

关 键 词:肾小管上皮  细胞凋亡  肾间质纤维化

Research Progress on Prevention and Control of Renal Tubular Cell Apoptosis in Renal Interstitial Fibrosis
YANG Ya-li,CHENG Xiao-xia. Research Progress on Prevention and Control of Renal Tubular Cell Apoptosis in Renal Interstitial Fibrosis[J]. International Journal of Traditional Chinese Medicine, 2009, 31(1). DOI: 10.3760/cma.j.issn.1673-4246.2009.01.041
Authors:YANG Ya-li  CHENG Xiao-xia
Abstract:Renal Tubular Cell Apoptosis refers to activation,proliferation,distension,cast formation and cellular apoptosis of the tubular epithelium when the renal tubule undergoes hypoxia,poisoning,inflammatory reaction,plasma protein or amylaceum.This text summarized the researches on the prevention and control of lenal tubular cell apoptosts in renal interstitial fibrosis in the recent years.
Keywords:Renal tubular cell  Apoptosis fibrosis
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