腹腔镜下广泛子宫切除联合盆腔淋巴结清扫术治疗早期宫颈癌近期疗效观察

目的：探讨腹腔镜下广泛子宫切除联合盆腔淋巴结清扫术治疗早期宫颈癌的近期临床疗效及安全性。方法：选取符合标准的患者80例，随机分为观察组和对照组各40例，对照组应用开腹广泛子宫切除术加盆腔淋巴结清扫术，观察组应用腹腔镜下广泛子宫切除联合盆腔淋巴结清扫术，比较二者临床治疗效果。结果：观察组患者手术时间长于对照组，但术中出血量、术后肛门排气时间、下床活动时间、拔除引流管时间、术后镇痛药使用率及术后住院时间等方面，均优于对照组，差异存在显著性（ P＜0．05）。两组患者淋巴结清扫数目及并发症发生率相似，差异无统计学意义（ P＞0．05）。术前两组患者FACT-G评分相似，差异无统计学意义（ P＞0．05）；术后3个月及6个月，两组患者FACT-G评分较术前均提高，差异存在显著性（ P＜0．05），但是观察组患者改善更显著（ P＜0．05）。结论：腹腔镜下广泛子宫切除联合盆腔淋巴结清扫术治疗早期宫颈癌近期临床疗效确切，手术创伤小、术后恢复快、安全可靠、有利于患者术后康复及提高生存质量。

Observation on the Short-term Effects of Laparoscopic Radical Hysterectomy Combined with Pelvic Lymph Node Dissection on Early Stage Cervical Cancer

Objective：To investigate the safety and short-term clinical effects of laparoscopic radical hysterectomy combined with pelvic lymph node dissection in treatment of early stage cervical cancer .Method：80 eligible patients were selected and randomly divided into observation group and control group , 40 patients in each group;the control group used open radical hysterectomy combined with pelvic lymph node dissection , while the observation group used laparoscopic radical hysterectomy combined with pelvic lymph node dissection , and the clinical therapeutic effects of the two groups were compared .Result：In the patients of the observation group , the operative time was longer than that of the control group , but the intra-operative blood loss, postoperative time of passage of gas by anus , out-of-bed activity time, time of extubating drainage tube, postoperative analgesics use percentage and postoperative length of stay and so on were all better than those of the control group, and the differences were statistically significant （P〈0.05）.The numbers of dissected lymph nodes and complications of the two groups were similar , and the differences were statistically insignificant （ P〉0.05） .The FACT-G scores of the patients of the two groups before the surgeries were similar, and the difference was statistically insignificant （ P〉0.05）;in 3 months and 6 months after the surgeries, the FACT-G scores of the patients of both groups were higher than those before the surgeries , and the differences were statistically significant （ P〈0.05 ） , but those of the patients of the observation group were improved more significantly （ P〈0.05） .Conclusion：Laparoscopic radical hysterectomy combined with pelvic lymph node dissection in treatment of early stage cervical cancer has positive short -term clinical therapeutic effects, small operation wound and rapid postoperative recovery , It is safe and reliable , and consequently is beneficial to the postoperative rehabilitation and elevating quality of life of the patients .