强化胰岛素治疗危重症患者应激性高血糖的临床疗效观察

目的：探讨危重症应激性高血糖（ SHG ）强化胰岛素治疗方案的疗效。方法：将120例危重症SHG患者随机分为强化胰岛素治疗组和常规治疗组各60例，观察两组治疗效果。结果：强化治疗组血糖水平均低于常规治疗组，P＜0．05；强化治疗组患者ICU治疗时间，抗生素使用时间，呼吸机使用时间，泵入胰岛素时间等优于对照组，均P＜0．05。两组治疗并发症主要包括院内感染和低血糖，其中，强化治疗组院内感染发生率低于对照组，P＜0．05；两组低血糖发生情况差异比较无统计学意义；两组死亡率比较差异有统计学意义，P＜0．05。结论：强化胰岛素治疗危重症SHG，具有较好的疗效，能有效降低并发症发生的几率，降低死亡率，临床疗效明显。mortality．

The Clinical Efficacy of Intensive Insulin Therapy for 60 Cases Critically ill Patients with Stress Hyperglycemia

Objective：To investigate the clinical efficacy of intensive insulin therapy for 60 cases criti-cally ill patients with stress hyperglycemia .Method：120 cases of critically ill patients were randomly divided into SHG intensive insulin therapy group and the conventional treatment group （60 cases, respectively）, and the effect were observed .Result： The blood glucose levels of the intensive therapy group were statistically lower than those of the conventional treatment group （ P＆lt;0.05 ） .The ICU treatment time , antibiotics use time, ventilation time and insulin pump time of the intensive therapy group were better than those of the con -trol group, all P＆lt;0.05.The complications included hypoglycemia and nosocomial infections , and the inci-dence of the both complications of the intensive therapy group were lower than that of the control group , （ P＆lt;0.05）.There was statistically significant of the mortality rate between the two groups , （P＆lt;0.05）.Conclu-sion：The clinical efficacy of intensive insulin therapy for 60 cases critically ill patients with stress hypergly-cemia is satisfactory , which could effectively reduce the probability of occurrence of complications and reduce mortality.