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实时组织弹性成像在乳腺肿瘤诊断中的应用
引用本文:张秀芳,刘学明,鲍晓峰,彭娴婧,张闻,许俊.实时组织弹性成像在乳腺肿瘤诊断中的应用[J].浙江大学学报(医学版),2006,35(4):444-447.
作者姓名:张秀芳  刘学明  鲍晓峰  彭娴婧  张闻  许俊
作者单位:浙江大学医学院,附属第二医院超声科,浙江,杭州,310009
摘    要:目的:探讨实时组织弹性成像(RTE)诊断乳腺肿瘤的应用价值。方法:对120例乳腺肿块患者,共135个病灶,先用B型图像和彩色多谱勒血流图(CDFI)检查,再行弹性成像检查,用5分法对弹性图进行评分。以手术后病理诊断结果为标准,分别计算应用弹性评分及二维超声表现结合弹性评分诊断乳腺恶性肿瘤的敏感性、特异性和一致性。结果:如弹性评分大于4分诊断乳腺恶性肿瘤敏感性为85.45%,特异性为83.75%,一致性为84.4%;应用二维超声表现结合弹性评分诊断乳腺恶性肿瘤的敏感性为100%,特异性为95%,一致性为97%。结论:RTE与二维图像相结合可提高乳腺恶性肿瘤的诊断正确性,具有良好的临床应用前景。

关 键 词:乳腺肿瘤/超声检查  超声检查  多普勒  彩色  实时组织弹性成像  诊断  鉴别
文章编号:1008-9292(2006)04-0444-04
收稿时间:2006-02-08
修稿时间:2006-04-12

Application of real-time tissue elastography in diagnosis of breast cancer
ZHANG Xiu-fang, LIU Xue-ming, BAO Xiao-feng, et al.Application of real-time tissue elastography in diagnosis of breast cancer[J].Journal of Zhejiang University(Medical Sciences),2006,35(4):444-447.
Authors:ZHANG Xiu-fang  LIU Xue-ming  BAO Xiao-feng  
Institution:Department of Ultrasonography, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China.
Abstract:Objective: To investigate the clinical value of real-time tissue elastography(RTE) in the diagnosis of breast cancer.Methods: One hundred and twenty patients with breast lumps(135 lesions) were examined with B-mode imaging,color Doppler flowing imaging(CDFI) and RTE.The elastogram was graded using 5-score evaluating method.The postoperative pathological diagnosis was used as gold standard,and the sensitivity,specificity and accuracy of RTE and two(-dimensional) ultrasonography combined with RTE in diagnosis of breast cancer were calculated.Results: When the score >4 was set for cut-off criteria of malignancy,the sensitivity,specificity and accuracy of RTE was 85.45%,83.75% and 84.4%,respectively.While two-dimensional ultrasonography combined with RTE was used,the sensitivity,specificity and accuracy increased up to 100%,95% and 97%,respectively.Conclusion: RTE combined with two-dimensional ultrasonography can improve the validity in the diagnosis of malignant breast lesions.
Keywords:Breast neoplasms/ultrasonogr  Ultrasonography  doppler  color  Elastography  Breast neoplasm  Diagnosis  differential
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