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Burden of Influenza-Associated Respiratory Hospitalizations,Vietnam, 2014–2016
Authors:Nguyen Cong Khanh  Ashley L. Fowlkes  Ngu Duy Nghia  Tran Nhu Duong  Ngo Huy Tu  Tran Anh Tu  Jeffrey W. McFarland  Thoa Thi Minh Nguyen  Nga Thu Ha  Philip L. Gould  Pham Ngoc Thanh  Nguyen Thi Huyen Trang  Vien Quang Mai  Phuc Nguyen Thi  Satoko Otsu  Eduardo Azziz-Baumgartner  Dang Duc Anh  A. Danielle Iuliano
Abstract:
Influenza burden estimates are essential to informing prevention and control policies. To complement recent influenza vaccine production capacity in Vietnam, we used acute respiratory infection (ARI) hospitalization data, severe acute respiratory infection (SARI) surveillance data, and provincial population data from 4 provinces representing Vietnam’s major regions during 2014–2016 to calculate provincial and national influenza-associated ARI and SARI hospitalization rates. We determined the proportion of ARI admissions meeting the World Health Organization SARI case definition through medical record review. The mean influenza-associated hospitalization rates per 100,000 population were 218 (95% uncertainty interval [UI] 197–238) for ARI and 134 (95% UI 119–149) for SARI. Influenza-associated SARI hospitalization rates per 100,000 population were highest among children <5 years of age (1,123; 95% UI 946–1,301) and adults >65 years of age (207; 95% UI 186–227), underscoring the need for prevention and control measures, such as vaccination, in these at-risk populations.
Keywords:influenza   burden   vaccines   incidence   hospitalization   viruses   respiratory infections   Vietnam
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