Antiseptic Compounds Still Active Against Bacterial Strains Isolated from Surgical Wound Infections Despite Increasing Antibiotic Resistance |
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| Authors: | A. Giacometti O. Cirioni G. Greganti A. Fineo R. Ghiselli M. Del Prete F. Mocchegiani B. Fileni F. Caselli E. Petrelli V. Saba G. Scalise |
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| Affiliation: | (1) Institute of Infectious Diseases and Public Health, University of Ancona, via Conca, 60020 Ancona, Italy,;(2) Department of General Surgery, I.N.R.C.A. I.R.R.C.S., University of Ancona, via della Montagnola, 60100 Ancona, Italy,;(3) Department of Infectious Diseases, San Salvatore Hospital, piazzale Cinelli, 60121 Pesaro, Italy, |
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| Abstract: | The in vitro activities of povidone iodine, potassium peroxymonosulfate, and dimethyldidecylammonium chloride were investigated against 379 nosocomial isolates of Staphylococcus aureus and Pseudomonas aeruginosa responsible for surgical wound infections in patients operated on between July 1995 and June 2001. Overall, the isolates were inhibited by the antiseptics at concentrations below those used routinely. In spite of increasing resistance to the various antibiotics used to treat surgical wound infections, no significant variation in the susceptibility to antiseptics was demonstrated during this 6-year study. Electronic Publication |
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