Properties of herpesvirus-induced "immediate early" polypeptides |
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| Authors: | R T Hay J Hay |
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| Affiliation: | Medical Research Council Virology Unit, Church Street, Glasgow G11 5JR, Scotland |
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| Abstract: | ![]()
It has been shown that both HSV1- and HSV2-induced “immediate early” polypeptides bind, with a range of affinities, to native calf thymus DNA in vitro. The biological relevance of this observation is reflected in cell fractionation studies, which demonstrate that HSV1-and HSV2-induced immediate early polypeptides migrate to the nucleus and there bind strongly to chromatin from infected cells. |
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| Keywords: | Author to whom reprint requests should be addressed. |
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