甲型血友病基因诊断及产前诊断的研究进展

甲型血友病是最常见的遗传性出血性疾病,受到了国内外研究者们的极大关注.由于此病尚无彻底根治方法,所以基因诊断及产前诊断显得尤为重要.基因诊断可分为直接基因诊断及间接连锁分析的方法;产前诊断的手段也在近年飞速发展.本文就直接基因诊断、间接连锁分析及产前诊断新技术这几方面的研究进展综述如下.

Advances in Gene Diagnosis and Prenatal Diagnosis of Hemophilia A

Hemophilia A is the most common hereditary hemorrhagic disease, which attracts great at-tention. Because we lack of effective curing methods for this disease, gene diagnosis and prenatal diagnosis ofhemophilia A become extremely important. The gene diagnosis includes direct gene diagnosis and indirect link-age analysis. The techniques of prenatal diagnosis for the disease have developed rapidly in resent years. Wereview the update on the gene diagnosis and prenatal diagnosis for Hemophilia A.