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支气管舒张试验对AECOPD小气道功能影响
引用本文:张帅,张虹霞,李晓辉,胥振扬.支气管舒张试验对AECOPD小气道功能影响[J].临床肺科杂志,2012,17(1):64-65.
作者姓名:张帅  张虹霞  李晓辉  胥振扬
作者单位:首都医科大学潞河教学医院呼吸内科,北京,101149
摘    要:目的 探讨支气管舒张试验对慢性阻塞性肺疾病急性加重期(AECOPD)小气道功能影响.方法 分析我院2008年1月至2011年4月38例AECOPD患者,行支气管舒张试验,FEV1、FEF 50%、FEF 75%、MMEF 75/25%行配对t检验.结果 支气管舒张试验在AECOPD及支气管舒张试验阳性组小气道功能均存在显著差异;在支气管舒张试验阴性组,FEV1、FEF 50%存在显著差异,但FEF 75%、MMEF 75/25%无差异.结论 支气管舒张试验可改善AECOPD患者小气道功能,但在支气管舒张试验阴性组小气道功能指标FEF 75%、MMEF 75/25%无改善.

关 键 词:慢性阻塞性肺疾病急性加重期  小气道功能  支气管舒张试验

The effect Of bronchodilation test on small airway function in AECOPD patients
ZHANG Shuai,ZHANG Hong-xia,LI Xiao-hui,XU Zhen-yang.The effect Of bronchodilation test on small airway function in AECOPD patients[J].Journal of Clinical Pulmonary Medicine,2012,17(1):64-65.
Authors:ZHANG Shuai  ZHANG Hong-xia  LI Xiao-hui  XU Zhen-yang
Institution:Captial Medical University Lu He jiao xue Hospital,Tongzhou,Beijing 101149,China
Abstract:Objective To assess the effect of bronchodilation test on small airway function in acute exacerbation chronic obstrctive pulmonary disease(AECOPD) patients.Methods In 38 patients with AECOPD in-hospital from January 2008 to April 2011,Bronchodilation test was determined,and FEV1,FEF 50%,FEF 75%,MMEF 75/25% were observed and analyzed as pairs by t-test.Results The parameters of small airway function had significant differences in AECOPD and the positive group;there were significant differences in FEV1 and FEF 50%,but there was no significant difference in FEF 75% and MMEF 75/25% in the negative group.Conclusion Small airway function was improved by bronchodilation test in AECOPD,but EF 75%,MMEF 75/25% were not improved obviously in the negative group.
Keywords:AECOPD  Small airway function  Bronchodilation test
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