| 西红花总苷的药理学研究Ⅰ.对炎症及免疫功能的影响 |
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| 引用本文： | 马世平,周素娣,舒斌,周锦祥. 西红花总苷的药理学研究Ⅰ.对炎症及免疫功能的影响[J]. 中草药, 1998, 0(8): 536-539 |
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| 作者姓名： | 马世平 周素娣 舒斌 周锦祥 |
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| 作者单位： | 中国药科大学!南京210009 |
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| 摘 要： | 西红花总苷ig明显抑制二甲苯所致小鼠急性耳廓肿胀、醋酸所致小鼠腹腔毛细血管通透性增高及蛋清、角叉菜胶所致大鼠足跖肿胀，且有一定的镇痛效应。对正常小鼠的免疫器官重量、非特异性免疫、特异性体液免疫功能无明显影响，但对迟发型变态反应有明显的抑制作用。
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| 关 键 词： | 西红花总苷 抗炎 镇痛 免疫功能 |
| 收稿时间： | 1997-12-18 |
Pharmacological studies Crocus Glycosides I .Effects on Antiinflammatory andImmune Function |
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| Ma Shiping,Zhou Sudi,Shu Bing. Pharmacological studies Crocus Glycosides I .Effects on Antiinflammatory andImmune Function[J]. Chinese Traditional and Herbal Drugs, 1998, 0(8): 536-539 |
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| Authors: | Ma Shiping Zhou Sudi Shu Bing |
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| Affiliation: | China Pharmaceutical University,Nanjing, 210009;China Pharmaceutical University,Nanjing, 210009;China Pharmaceutical University,Nanjing, 210009;China Pharmaceutical University,Nanjing, 210009 |
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| Abstract: | Crocins (CC), 500mg/kg (ig),inhibited the swelling of mouse ear induced by xylene, the increase of capillary permeability and writhing induced by acetic acid in mice,at 50mg/kg inhibited the edema ofhind paw induced by carrageenan and fresh egg white in rats. The weights of thymus and spleen,and humoral immune response were not significantly influenced. At the dose of 200mg/kg,CC inhibited footpad reaction induced by sheep red blood cells (SRBC),and markedly inhibited contact dermatitis induced by picryl chloride. |
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| Keywords: | Crocins antiinflammatory immune function |
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