| 叶黄素对老年性黄斑变性预防及治疗作用的Meta分析 |
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| 引用本文： | 张福东,王俐,蔡美琴. 叶黄素对老年性黄斑变性预防及治疗作用的Meta分析[J]. 中华临床营养杂志, 2010, 18(2): 126-130,I0001. DOI: 10.3760/cma.j.issn.1674-635X.2010.02.015 |
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| 作者姓名： | 张福东 王俐 蔡美琴 |
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| 作者单位： | 上海交通大学医学院营养系,200025 |
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| 摘 要： | 目的评价叶黄素对老年性黄斑变性（AMD）的预防及治疗作用。方法采用电子检索、手工检索及索引检索方式检索所有叶黄素对AMD预防及治疗作用的病例对照研究、队列研究的中英文研究文献，对纳入文献进行质量评价后提取数据信息，采用专用软件RevMan4．2完成系统评价过程。结果共纳入9篇临床研究，合并OR为0．81（0．71，0．92）。结论叶黄素可以在一定程度上预防AMD的发生或延缓其发展。
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| 关 键 词： | 叶黄素 老年性黄斑变性 Meta分析 |
Role of lutein in preventing/slowing down age-related macular degeneration: a Meta-analysis |
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| ZHANG Fu-dong. Role of lutein in preventing/slowing down age-related macular degeneration: a Meta-analysis[J]. Chinese Journal of Clinical Nutrition, 2010, 18(2): 126-130,I0001. DOI: 10.3760/cma.j.issn.1674-635X.2010.02.015 |
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| Authors: | ZHANG Fu-dong |
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| Affiliation: | .(Department of Nutrition, Medical College, Shanghai Jiaotong University, Shanghai 200025, China) |
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| Abstract: | Objective To evaluate the role of lutein in preventing and slowing down age-related macular degeneration (AMD). Methods Literatures concerning lutein and AMD were collected by computerized search, manual search, expert consultations. The quality of included studies was evaluated. RevMan software 4.2was used for meta-analysis. Results Totally 9 studies were included, with a total OR of 0. 81 (range: 0. 71-0.92). Conclusion Lutein can, to some extent, prevent or slow down AMD. |
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| Keywords: | Lutein/Zeaxanthin Age-related macular degeneration Meta-analysis |
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