原发性中枢神经系统淋巴瘤临床病理及免疫组化研究

[目的]探讨原发性中枢神经系统恶性淋巴瘤(PCNSI。)的病理学特点。[方法]收集10例PCNSL病人的临床资料，并进行病理形态及免疫组化分析。[结果]PCNSL病理形态及免疫组化结果提示均为B细胞性淋巴瘤，其中8例为弥漫性大B细胞淋巴瘤，2例为小淋巴细胞性淋巴瘤。[结论]PCNSL是少见的颅内肿瘤，绝大部分为B细胞性，其亲血管性常形成血管袖套状结构。免疫组化在诊断与鉴别诊断中起着重要作用。

The Clinicopathological Features and Immunohistochemical Study of Primary Lymphoma of Central Nervous System

To investigate the clinicopathological features of primary central nervous sys-tem lymphoma(PCNSL).Data of10cases with PCNSL were collected,and pathological morphology and immunohistochemical results were analysed.The pathological morpholo-gy and immunohistochemical results showed that all the10cases were B-cell lymphoma.Among them,8cases were diffuse large B-cell lymphoma,2cases were B-small type.[Conclusions]The PCNSL is rare and highly malignant tumor in the brain.The majority of PCNSL were derived from B cells.The tumor cells surround and involve vessels forming cuffing.Immunohistochemistry plays an important role in diagnosis of PCNSL.