| 星形细胞瘤微血管密度与病理分级的相关性 |
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| 引用本文： | 张辉,周康荣,刘起旺,杨晓棠,钱丽霞,梁力,张锁旺,孙少杰,徐坚定.星形细胞瘤微血管密度与病理分级的相关性[J].山西医科大学学报,2001,32(5):405-406. |
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| 作者姓名： | 张辉 周康荣 刘起旺 杨晓棠 钱丽霞 梁力 张锁旺 孙少杰 徐坚定 |
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| 作者单位： | 1. 山西医科大学第一临床医学院放射科,
2. 复旦大学医学院附属中山医院放射科 |
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| 摘 要： | 目的 探讨星形细胞瘤微血管密度（MVD）与病理分级的关系。方法 对磁共振成像（MRI）术前诊断及手术病理证实的幕上星形细胞瘤石蜡标本进行免疫组化染色，测定MVD。结果 随着星形细胞瘤级别的增加，MVD值增高，且Ⅰ、Ⅱ级与Ⅲ、Ⅳ级之间有显著差异（P＜0．01）；MVD随着肿瘤直径增大而增加，但无显著差异（P＞0．05）。结论 MVD与星形细胞瘤恶性表型及生物学行为密切相关，可作为判断星形细胞瘤恶性程度的指标。
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| 关 键 词： | 星形细胞瘤 微血管密度 病理分级 磁共振成像 |
| 文章编号： | 1007-6611(2001)05-0405-02 |
Correlation between microvessel density and pathologic grading in astrocytoma |
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| ZHANG Hui,ZHOU Kang rong,LIU Qi wang,et al.Correlation between microvessel density and pathologic grading in astrocytoma[J].Journal of Shanxi Medical University,2001,32(5):405-406. |
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| Authors: | ZHANG Hui ZHOU Kang rong LIU Qi wang |
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| Abstract: | Objective To study the correlation of microvessel density (MVD) and pathologic grading in astrocytomas. Method Sixty eight cases of astrocytomas proved by surgery and pathology were examined with 0 5 T MR system and MVD were measured by immunohistochemical method. Results As the pathologic grading increased, MVD value was more higher ( P <0 01),but not related to tumor size ( P >0 05). Conclusion The MVD is significantly correlative with malignant degree and biological behavior of astrocytomas, and may use as an indicator of determining malignant degree in astrocytomas. |
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| Keywords: | astrocytoma microvessel density pathologic grading magnetic resonance imaging |
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