复方苦参漱口液对口腔常见致病菌的抑制作用

目的:研究复方苦参漱口液对口腔常见致病菌的体外抑制作用。方法:对嗜酸乳杆菌等6种口腔常见致病菌的标准菌株采用培养基体外培养增殖,测定苦参漱口液的最低抑菌浓度、MIC50、MIC90;平板法测定抑菌强度,并与茶多酚作比较。结果:复方苦参漱口液对6种标准菌株的最低抑菌浓度均低于原液浓度。对致龋菌,复方苦参漱口液取得与茶多酚相似的抑菌效果;对黏膜致病菌,复方苦参漱口液的抑菌作用强于茶多酚。平板抑菌环结果:复方苦参漱口液和茶多酚之间比较无显著差异。结论:复方苦参漱口液有良好的抑菌作用。

The inhibition of compound lightyellow sophora root collutory on oral bacteria

PURPOSE:To study the inhibition of compound lightyellow sophora root collutory on oral bacteria.METHODS:The standard strains of common oral bacteria were cultured and proliferated by corresponding media in vitro.The minimum inhibitory concentration(MIC),MIC50,MIC90 of compound lightyellow sophora root collutory were determined.The bacteriostatic effects were determined by the plating method.RESULTS:The MIC of compound lightyellow sophora root collutory were lower than the stock solution concentration.It was showed that compound lightyellow sophora root collutory had the same effect as tea polyphenol on oral bacteria.To Actinomyces naeslundii,compound lightyellow sophora root collutory inhibited the bacteria growth more obviously than tea polyphenol.The result showed that there was no remarkable difference between the compound lightyellow sophora root collutory and tea polyphenol by the plating method.CONCLUSION:Compound lightyellow sophora root collutory can inhibit the oral bacteria growth obviously.Supported by Research Fund of Science and Technology Committee of Shanghai Municipality(034119924).