溴化N-甲基阿托品扩瞳与睫状肌麻痹作用的实验研究 |
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引用本文: | 徐介文,张作华,李书桐,高丹宇,李军. 溴化N-甲基阿托品扩瞳与睫状肌麻痹作用的实验研究[J]. 中国药理学通报, 1989, 0(4) |
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作者姓名: | 徐介文 张作华 李书桐 高丹宇 李军 |
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作者单位: | 空军西安医院 空军西安医院 西安 |
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摘 要: | 溴化N-甲基阿托品(简称AMB),家兔扩瞳试验和离体猫睫状肌麻痹试验证明:AMB有较强的扩瞳作用;对由乙酰胆碱引起的睫状肌收缩,松弛效果快,强于硫酸阿托品、氢溴酸、后马托品和妥品酰胺。AMB对睫状肌的结合力远小于阿托品和后马托品,稍大于妥品酰胺。说明AMB属一种速效、短效的扩瞳与睫状肌麻痹剂。
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关 键 词: | 溴甲阿托品 扩瞳 麻痹睫状肌 乙酰胆碱 速效 短效 |
THE MYDRIASIS & CILIARE MUSCLE PARALYSIS EFFECT OF ATROPINE METHOBROMIDE |
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Abstract: | The experiments of rabbit mydriasis & isolated cat ciliare muscle paralysis of atropine Methobromide (AMB) have demonstrated that : AMB has much larger mydriasis effect. It effects faster than Atropine Sulfate, Homatropine & Tropinexamide in acetylcholin -induced ciliare muscle contraction. The combined-force of AMB on ciliare muscle is less than Atropine & Homatropine, but a little larger than Tropinexamide. There fore AMB is a rapid & short-time mydriasis agent & ciliare muscle paralysis agent. |
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Keywords: | Atropine Methobromide Mydriasis Ciliare muscle paralysis Acetylcholin rapid short-time |
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