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| Selective inhibition of Hepatocarcinoma cells by apatite nanoparticles | |
| 引用本文： | SUN En jie 1,LI Shi pu 2,YAN Yu hua 2 CAO Xian ying 2,FENG Ling yun 2,XIONG Xian li 2,ZHANG Zhu 2 1 College of Materials Science and Engineering 2 Biomedical Materials And Engineering Center Wuhan University of Science and Technol. Selective inhibition of Hepatocarcinoma cells by apatite nanoparticles[J]. 中国生物医学工程学报(英文版), 2002, 0(2) |
| 作者姓名： | SUN En jie 1 LI Shi pu 2 YAN Yu hua 2 CAO Xian ying 2 FENG Ling yun 2 XIONG Xian li 2 ZHANG Zhu 2 1 College of Materials Science and Engineering 2 Biomedical Materials And Engineering Center Wuhan University of Science and Technol |
| 作者单位： | SUN En jie 1，LI Shi pu 2，YAN Yu hua 2 CAO Xian ying 2，FENG Ling yun 2，XIONG Xian li 2，ZHANG Zhu 2 1 College of Materials Science and Engineering 2 Biomedical Materials And Engineering Center Wuhan University of Science and Technol |
| 基金项目： | the National Science Foundation of China( No.3 9770 2 2 5)，China postdoctoral Science Foundation |
| 摘 要： | In 1 994,Hideki Aoki and his colleagues happened to find that apatite (HAP)nanoparticlesinhibited growth of cancer cells when they tried to determine the possi-bility for HAP nanoparticles to act as tumor suppressing drugs carrier〔1〕.LaterShipu Li etal.… |
Selective inhibition of Hepatocarcinoma cells by apatite nanoparticles |
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| SUN En jie ,LI Shi pu ,YAN Yu hua CAO Xian ying ,FENG Ling yun ,XIONG Xian li ,ZHANG Zhu College of Materials Science and Engineering Biomedical Materials And Engineering Center Wuhan University of Science and Technol. Selective inhibition of Hepatocarcinoma cells by apatite nanoparticles[J]. Chinese Journal of Biomedical Engineering, 2002, 0(2) | |
| Authors: | SUN En jie LI Shi pu YAN Yu hua CAO Xian ying FENG Ling yun XIONG Xian li ZHANG Zhu College of Materials Science Engineering Biomedical Materials And Engineering Center Wuhan University of Science Technol |
| Affiliation: | SUN En jie 1,LI Shi pu 2,YAN Yu hua 2 CAO Xian ying 2,FENG Ling yun 2,XIONG Xian li 2,ZHANG Zhu 2 1 College of Materials Science and Engineering 2 Biomedical Materials And Engineering Center Wuhan University of Science and Technol |
| Abstract: | The effects of HAP nanoparticles on growth of primary normal animal liver cells and on growth of hepatocarcinoma cell line Bel 7402 in vitro were studied respectively and were compared with each other.The results showed that HAP nanoparticles in certain concentration inhibited growth of cancer cells significantly while did not inhibite normal cells in the same concentration.The inhibition ratio was as high as very high dosage of adriamycin.It was concluded that HAP nanoparticles can selectively inhibited cancer cells. |
| Keywords: | HAP nanoparticles cancer cells inhibition of cancer cell |
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