孟鲁斯特钠治疗小儿支气管哮喘疗效观察

目的观察孟鲁斯特钠治疗小儿支气管哮喘的临床疗效。方法将80例支气管哮喘患儿随机分为治疗组和对照组各40例。对照组给予常规吸入糖皮质激素治疗,治疗组在对照组的基础上给予孟鲁司特钠口服。观察2组临床疗效和咳嗽缓解、消失时间。结果治疗组总有效率为97.5%高于对照组的85.0%,差异有统计学意义(P<0.05);治疗组咳嗽缓解时间及咳嗽消失时间明显短于对照组,差异均有统计学意义(P<0.05)。结论在吸入糖皮质激素治疗基础上加用孟鲁斯特钠治疗小儿支气管哮喘疗效显著,值得临床推广应用。

The effect observation of montelukast sodium in treatment of children with bronchial asthma

Objective To observe the clinical effect of montelukast sodium in treatment of children with bronchial asthma.Methods 80 cases patients of children with bronchial asthma were randomly divided into treatment group and control group,each of 40 cases.Control group were given conventional treatment of inhaled corticosteroids;On the basis of control group,treatment group were given montelukast sodium.Observed the cough relief and disappear time and clinical effect of two groups.Results The total effective rate of the treatment group（97.5%） was higher than that of the control group（85.0%）,the difference was statistically significant（P0.05）;Cough relief and disappeared cough time of the treatment group was significantly shorter than that of the control group,the difference was statistically significant（P0.05）.Conclusion On the basis of inhaled glucocorticoid,montelukast sodium in treatment of bronchial asthma in children has a significant effect,is worthy of clinical application.