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石榴汁和苹果汁干预对老龄大鼠肝、心、脑组织自由基代谢的影响
引用本文:徐静,刁焕荣,拱玉华,郭长江,韦京豫,杨继军. 石榴汁和苹果汁干预对老龄大鼠肝、心、脑组织自由基代谢的影响[J]. 中国慢性病预防与控制, 2011, 19(2): 185-187
作者姓名:徐静  刁焕荣  拱玉华  郭长江  韦京豫  杨继军
作者单位:1. 沈阳军区总医院营养科,辽宁,110016
2. 中国医科大学附属第四医院肿瘤放疗科
3. 军事医学科学院卫生学环境医学研究所营养研究室
摘    要:目的研究抗氧化活性较强的石榴汁和较弱的苹果汁对老龄大鼠肝、心、脑组织自由基代谢的影响。方法自然衰老Wistar大鼠(22月龄)30只,随机分为三组,分别灌胃石榴汁3.2ml,苹果汁2.4ml和蒸馏水3.2ml(对照组),实验周期4周,实验结束后取大鼠肝、心、脑组织制作匀浆液测定总抗氧化力、丙二醛(MDA)及自由基含量。结果石榴汁干预组老龄大鼠肝脏、脑组织抗氧化能力显著升高、自由基水平明显下降,肝、心、脑MDA含量均显著降低,与对照组比较差异有统计学意义;苹果汁于预后老龄大鼠肝组织MDA含量及自由基水平明显降低。苹果汁、石榴汁对老龄大鼠心脏抗氧化能力及自由基水平均无显著性影响。结论抗氧化活性较高的石榴汁改善衰老大鼠肝、心、脑组织自由基代谢能力较强,而抗氧化活性较低的苹果汁作用稍弱。

关 键 词:石榴汁  苹果汁  衰老  自由基

Effect of Pomegranate Juice and Apple Juice on Free Radical Metabolism in Liver,Heart and Brain of Aged Rats
XU Jing,DIAO Huan-rong,GONG Yu-hua,et al.. Effect of Pomegranate Juice and Apple Juice on Free Radical Metabolism in Liver,Heart and Brain of Aged Rats[J]. Chinese Journal of Prevention and Control of Chronic Non-Communicable Diseases, 2011, 19(2): 185-187
Authors:XU Jing  DIAO Huan-rong  GONG Yu-hua  et al.
Affiliation:XU Jing,DIAO Huan-rong,GONG Yu-hua,et al.Department of Nutrition,General Hospital of Shenyang Military Region,PLA,Shenyang 110016,China
Abstract:Objective To study the effect of pomegranate juice and apple juice on free radical metabolism in the liver,heart and brain tissues of aged rats.Methods Thirty aged Wistar rats(22 months old) were randomly divided into three groups: pomegranate juice and apple juice as two experimental groups,while distilled water as normal control group.They were administrated fruit juices or distilled water respectively by gavage daily for 4 weeks.At the end of experiment,total antioxidant capacity(TAOC),content of MDA and...
Keywords:Pomegranate juice  Apple juice  Aging  Free radical  
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