A comparison of baseline and induced DNA damage in human spermatozoa from fertile and infertile men, using a modified comet assay |
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| Authors: | Hughes, Ciara M. Lewis, Sheena E.M. McKelvey-Martin, Valerie J. Thompson, W. |
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| Affiliation: | 1 Department of Obstetrics and Gynaecology, The Queen's University of Belfast, Institute of Clinical Science Grosvenor Road, Belfast BT12 6BJ 2 Department of Cancer and Ageing Research Group, School of Biomedical Sciences, The University of Ulster Coleraine, UK |
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| Abstract: | ![]()
Baseline DNA damage in spermatozoa from fertile and infertilemen was compared using a modified alkali single cell gel electrophoresis(comet) assay. Semen from normozoospermic fertile, normozoospermicinfertile and asthenozoospermic infertile (World Health Organizationcriteria, 1992) samples were studied. No significant differencewas observed in levels of baseline damage between the threegroups. A median value for baseline damage of |
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